How to Edit/change and save the value of Internal Memory

Are you talking about this in your target hardware, or just how to do it in the Simulator?

When you say "Reset", is that just a reset (without power-cycle), or must it also include a power-cycle?

For target hardware, and to save data over a power-cycle, You need to provide some sort of Non-Volatile storage - there are many possibilities; eg:
FRAM
EEPROM
Battery-backed SRAM
Flash

Are you talking about this in your target hardware, or just how to do it in the Simulator?

When you say "Reset", is that just a reset (without power-cycle), or must it also include a power-cycle?

For target hardware, and to save data over a power-cycle, You need to provide some sort of Non-Volatile storage - there are many possibilities; eg:
FRAM
EEPROM
Battery-backed SRAM
Flash

No no Sir,

Am asking during Simulation...Some Internal Memories are changing constantly...Please say how to restore these values...

http://www.keil.com/support/man/docs/uv3/uv3_cm_save.htm

http://www.keil.com/support/man/docs/uv3/uv3_cm_load.htm

"Some Internal Memories are changing constantly"

Of course they are!
It in is the very nature of programs that they use memory; therefore you should expect that memory contents should change constantly as the program executes!

It is also in the nature of memories that their content is undefined at start-up; if your software relies upon certain values being present in the memory at start-up, then you need to write code to do that.
This is called Initialisation.

eg, see http://www.keil.com/support/man/docs/c51/c51_ap_startup.htm and the associated knowledgebase articles.