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Any one help me .im interfacing i2c based eeprom to lpc1248 my problem is i connect the pullup resister 3.3v to only SCL pin and not connect SDA line is it possible to achive the communication
Not likely, I2C lines are Open Drain meaning they can only sink current (logic 0) or hi-z (line floats). They need the pull ups so when it is in the hi-z state, you get a nice sharp (depending on resistor size) rising edge to Vcc.
Your device may offer some kind of internal pull-up that you can enable, this is probably your only bet other than modifying your board. Check your datasheet.
en.wikipedia.org/.../I²C en.wikipedia.org/.../Open_drain
thanks