Blank open After compilation or same time later with the MDK-ARM5.43

As i say in title ,I'm using the new version and the new compiler. After using the software for some time, when I open the files, they become blank. Turn off, then turn on again, and it will return to normal.as well as ,I have an encryption software installed on my computer, Could you tell me if this has any impact?When to solve the problem with the new software?Thanks.