Keil MDK Simulation keeps executing the first line assembly code

I tried to simulate the instruction execution on Arduino nano 33 ble sense. So using Keil MDK, I selected nrf52480 as a device for simulation and used the initialization file to debug from the main function. But when I started debug session, the simulation stayed at the first line assembly code at the address 0x00000000. I doubted that I haven't set up the right value of CPU DLL and Dialog DLL. The default value of CPU DLL is "SARMCM3.DLL -MPU" and that of Dialog DLL is "DCM.DLL -pCM4". Very appreciate it if someone can answer my question. 

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